4 edition of Cell lineage, stem cells, and cell determination found in the catalog.
Cell lineage, stem cells, and cell determination
International Workshop on Cell Lineage, Stem Cells, and Cell Determination (1979 Seillac, France)
by North-Holland Pub. Co., sole distributors for the USA and Canada, Elsevier North Holland in Amsterdam, New York, New York
Includes bibliographical references and index.
|Statement||sponsored by the Institut national de la santé et de la recherche médicale, the European Molecular Biology Organization, and the International Society of Developmental Biologists ; editor, N. Le Douarin.|
|Series||Inserm symposium ;, no. 10, INSERM symposium ;, no. 10.|
|Contributions||Le Douarin, Nicole, 1930-, Institut national de la santé et de la recherche médicale (France), European Molecular Biology Organization., International Society of Developmental Biologists.|
|LC Classifications||QL963.5 .I55 1979|
|The Physical Object|
|Pagination||xv, 378 p. :|
|Number of Pages||378|
|LC Control Number||79020701|
Get this from a library! Cell lineage, stem cells, and cell determination: proceedings of the International Workshop on Cell Lineage, Stem Cells, and Cell Determination, held in Seillac, . This book gives you all the important information you need to become a stem cell scientist. It covers the characterization of cells, genetic techniques for modifying cells and organisms, tissue culture technology, transplantation immunology, properties of pluripotent and tissue specific stem cells .
LONDON, Aug. 24, /PRNewswire/ -- The global stem cell technologies and applications market is estimated to have reached US $17, million and is expected to grow . Hisato Kondoh, in Mouse Development, F Retinal Stem Cells. Cell lineage and clonal analyses of development of the retinal cells have been successfully carried out by labeling progenitors of various stages of development using replication-incompetent retroviral vectors (Turner, et al., ).During the earliest phase of retina development following optic cup formation, extensive cell.
Multiple cell populations, represented by distinct markers including Lgr5 and Bmi1, are capable of reconstituting the intestinal epithelium. Using comparative RNA-sequencing and single-cell transcriptomics, Yan et al. define Bmi1-GFP+ and Prox1+ cells as enteroendocrine lineage cells that possess intestinal stem cell . Cell lineage denotes the developmental history of a tissue or organ from the fertilized embryo. This is based on the tracking of an organism's cellular ancestry due to the cell divisions and relocation as time progresses, this starts with the originator cells and finishing with a mature cell .
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For the purposes of stem cell studies, the key step in lineage analysis is identifying stem cell clones. Most dividing cells that are marked in a lineage experiment are not stem cells. Non-stem cells generate clones known as transient clones, that tend to be variable in size because they commence at every point along the lineage.
An important feature of retina development revealed by the cell-labeling technique is that cell type determination is totally independent of the cell lineage (Turner, et stem cells, ).
The progenitor cells remain multipotential and both daughter cells continue the cell. Robert K Cell lineage PhD, in Gastroenterology and Nutrition: Neonatology Questions and Controversies, Lineage Determination. The four cell lineages of the small intestine arise from the stem cell. A number of different approaches have identified Notch signaling as a key step in lineage.
Clonal marking methods represent one of the most powerful tools available for identifying stem cells and analyzing their function. Derived from classical approaches in cell lineage tracing during development, we review modern cell lineage methods and describe how they are used to identify stem cells and their niches.
We discuss key considerations a stem cell Cited by: Cell fate. The development of new molecular tools including GFP, and major advances in imaging technology including fluorescence microscopy, have made possible the mapping of the cell lineage of Caenorhabditis elegans including its embryo.
This technique of fate mapping is used to study cells as they differentiate and gain specified function. Merely observing a cell.
The embryonic stem cell circuit. In a dynamical model was developed for the core embryonic stem cell network which comprises Oct4, Sox2 and Nanog.
It was found that cooperative interactions between these TFs give rise to a bistable switch-like behavior. One key prediction of the resulting dynamics is that over-expression of Nanog can maintain pluripotency of the cell. This study reports a comprehensive characterization of stomatal lineage cell development using single-cell transcriptome analysis.
The authors identified the cell types and marker genes of stomatal lineage cells, and revealed the transcriptional networks that regulate the differentiation from meristemoid mother cells to guard mother cells.
Mouse and human embryonic stem cells. The first forays into understanding pluripotency in the mammalian embryo began with rather simple experiments in which pieces of mouse germ cell tumors known as teratocarcinomas were grown in culture and a variety of pluripotent cell types emerged (Solder, ).One cell type, termed Embryonal Carcinoma Cells.
A notable variation of this process of lineage specification is the persistence of Pou5f1 activity throughout the differentiation of the primordial germ cells, which may underpin their ability to produce pluripotent progeny either as stem cells (embryonic germ cells.
Neural crest cells are multipotent stem cells that give rise to various cell lineages. A number of signaling molecules, including Wnts, transforming growth factor-β, and Notch, promote the specification of particular cell fates in neural crest cells.
Using single-cell lineage tracing, the authors identify TCF15 as a novel regulator of haematopoietic stem cell quiescence and self-renewal. New discoveries in the field of stem cell research have frequently appeared in the news and in scientific literature.
Research in this area promises to lead to new therapies for cancer, heart disease, diabetes. Abstract. Hematopoietic stem cells (HSCs) have self-renewal activity and multipotency.
Clonal analysis and determination of HSC differentiation potential into platelets and erythrocytes as well as leukocytes are essential for the study of self-renewal and lineage.
PAX6 is a master regulatory gene involved in neuronal cell fate specification. It also plays a critical role in early eye field and subsequent limbal stem cell (LSC) determination during eye. However, the underlying mechanisms of stem cell fate specification are unclear. Chirality is one of the most crucial factors that affects stem cell development and is implicated in asymmetrical cell morphology formation; however, its function in heterogeneous cell fate determination.
A germ cell is any biological cell that gives rise to the gametes of an organism that reproduces many animals, the germ cells originate in the primitive streak and migrate via the gut of an embryo to the developingthey undergo meiosis, followed by cellular differentiation into mature gametes, either eggs or animals, plants do not have germ cells.
A novel role of angiotensin II in epidermal cell lineage determination: Angiotensin II promotes the differentiation of mesenchymal stem cells into keratinocytes through the p38 MAPK, JNK and JAK2.
Introduction. Tissue niches are essential for controlling stem cell self-renewal and differentiation (Voog and Jones, ).Epithelial lineages in the skin are maintained by stem cells that exist in multiple tissue microenvironments (Blanpain and Fuchs, ).In particular, the niche for hair follicle stem cells.
Adult tissue stem cells (SCs) reside in niches, which, through intercellular contacts and signaling, influence SC behavior. Once activated, SCs typically give rise to short-lived transit-amplifying cells (TACs), which then progress to differentiate into their lineages.
Here, using single-cell. SOX2 has a crucial role in the lineage determination and proliferation of mesenchymal stem cells through Dickkopf-1 and c-MYC Cell Death Differ. Mar;19(3) doi: /cdd. The gonad is a unique biological system for studying cell-fate decisions.
However, major questions remain regarding the identity of somatic progenitor cells and the transcriptional events driving cell differentiation. Using time-series single-cell .Genetic lineage tracing based on Cre-loxP recombination provides an effective strategy for inferring cell fate and cell conversion in vivo.
However, the determination of t Unraveling the fates of resident stem cells .Cell labeling and lineage tracing in zebrafish gastrula stage embryos has demonstrated that cells destined to form the pronephros arise from the ventrolateral mesoderm, in a region partially overlapping with cells fated to form blood (Fig.
3 A) (Kimmel, Warga, & Schilling, ).These cells .